Patrick Pollak

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Pathological Anatomy. Illustrations of the Elementary Forms of Disease.

First issued as 12 separate fascicules between January 1833 and January 1838, then in book form in 1838 in possibly only 300 copies. The text comprises four preliminary leaves [4] and a varying number of leaves for each of 12 subjects, with 4 handcoloured lithographed plates for each subject. These are : INFLAMMATION [8] -:- ANALOGOUS TISSUE [12] -:- ATROPHY [9] -:- HYPERTROPHY [8] -:- PUS [8] -:- MORTIFICATION [12] -:- HEMORRAGE (sic) [8] -:- SOFTENING [8] -:- MELANOMA [8] -:- HETEROLOGOUS FORMATIONS - CARCINOMA [15] -:- TUBERCLE [7]. The bracketed numbers are the number of text leaves per fascicule. The total number of text leaves here is 107, of 109 - the pages are not numbered and there is no standard registration of the leaves. The 2 leaves wanting are the divisional titles for the sections CARCINOMA and TUBERCLE. Each fascicule has 4 plates, as called for, thus 48 plates in total. Contemporary half calf and marbled boards, newly rebacked, spine with raised bands, a few plates without tissue guards and some plates foxed, some plates with pencilled identification by SIR GEORGE MURRAY HUMPHRY whose gift label is on the front paste-down, overall a very good copy.

*Wellcome II, p. 306; Norman 408; G&M 2291; HEIRS OF HIPPOCRATES #871 - 'This striking work is rightly regarded as one of the finest pathological atlases ever produced. It is rivalled for beauty and accuracy only by Cruveilhier's Anatomie pathologique du corps humaine. The drawings are taken from a set of 2000 watercolour paintings of diseased structures which remain at University College where Carswell was Professor of Anatomy.' ; PETER THOMAS Medicine & Science at Exeter Cathedral Library: #C23; OSLER #2250 - 'These illustrations have, for artistic merit and for fidelity, never been surpassed, while the matter represents the highest point which the science of morbid anatomy had reached before the introduction of the microscope.' SEE ALSO : ALASTAIR COMPSTON. J Neurol Neurosurg Psychiatry. 1988 Oct; 51(10): 12491252. The 150th Anniversary of the first depiction of the lesions of multiple sclerosis. The clinical and pathological features of multiple sclerosis were fully described, in France and subsequently in England, during the latter half of the XIXth century but clinical descriptions, personal accounts and depictions of the disease had appeared at various times over the previous 50 years. Jean Cruveilhier is usually credited with having first illustrated the lesions of multiple sclerosis in the second tome of his pathological atlas which bears the title date 1835. But the 40 livraisons which make up this work were published separately in parts and documentary evidence contained within the second volume indicates that the putative case of multiple sclerosis cannot have appeared earlier than 1841. Robert Carswell also may have published his pathological atlas in parts but the work was completed by 1838 and so his depiction of the lesions of multiple sclerosis, appearing on plate 4 fig 1, predates Cruveilhier's by at least three years. Curiously, Carswell and Cruveilhier each observed their pathological material in Paris but they cannot have depicted the same individual. 1988 is therefore the 150th anniversary of the depiction of the lesions of multiple sclerosis; the unnamed patient was French, the illustrator a Scotsman.

Longman, Orme, Brown, Green and Longman. London.

Date Published: 1838. Folio.

Stock No. 62470

Price: 10,000.00