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Appointed to Investigate the Physiological and Therapeutical Effects of the Hypodermic Method of Injection.

pp. (561)-643, (i). An extract in new paper wrappers, in very good condition.

*FRANCIS RYND (1801-1861), an Irish physician, invented the hollow needle in 1844, and made the first recorded subcutaneous injections of a sedative to treat neuralgia [see G-M#1968 for his paper in the 'Dublin Medical Press',1845 'Neuralgia - introduction of fluid to the nerve.']. The medical hypodermic syringe was developed simultaneously by ALEXANDER WOOD (1817-1884) in Edinburgh, and CHARLES GABRIEL PRAVIZ, of Lyons (1791-1853). By 1853 they had each developed an instrument with a needle fine enough to pierce the skin. Wood's paper in the Edinburgh Medical and Surgical Journal described it in therapeutic use- 'A New Method of treating Neuralgia by the direct application of Opiates to the Painful Joints', [see G-M#1969, 1855]. Shortly thereafter, the first recorded fatality from a hypodermic syringe induced overdose was Wood's wife from self administered morphine. The Committee above was chaired by W. S. SAVORY, with the help of HOLMES, BOSTOCK, HULKE and others. Alexander Wood had been asked to participate but had declined. Their conclusions had been drawn from 1. Original experiments on animals and man, 2. Personal evidence of experienced medical men, and 3. Records of fact and other communications in answer to a series of questions posed in the Medical Journals.

Vol. L (50) of an unknown Journal.

Date Published: No date [c.1867].

Stock No. 57340

Price: 125.00